Emerging Opioid: Cychlorphine Edition
Public health and safety partners nationwide are warning about cychlorphine, an emerging synthetic opioid identified in the illicit drug supply across the United States. Cychlorphine belongs to a class of novel synthetic opioids known as “orphines.” It has been found on its own and in combination with fentanyl and other substances, including methamphetamine, cocaine, and counterfeit pills made to resemble prescription medications.
Why is it dangerous?
Cychlorphine may be up to 10 times more potent than fentanyl, and overdoses may require multiple doses of naloxone. Importantly, cychlorphine is not detected by common drug test strips, including fentanyl test strips, or routine hospital opioid urine screens, meaning comprehensive toxicology testing may be needed to confirm exposure.
Routine testing may not identify cychlorphine; a negative test does not rule out opioid exposure.
How can you stay safe?
Carry naloxone and know how to use it. Know the signs of an overdose. If an overdose is suspected, administer naloxone and call 911 immediately.